Counties with highest COVID-19 infection rates in South Carolina
compiled a list of counties with the highest COVID-19 infection rates in South Carolina using data from U.S. Department of Health & Human Services.
Counties with highest COVID-19 infection rates in South Carolina
Updated
The vaccine deployment in December 2020 signaled a turning point in the COVID-19 pandemic. By the end of May 2021, 40% of the U.S. population was fully vaccinated. But as vaccination rates lagged over the summer, new surges of COVID-19 came, including Delta in the summer of 2021, and now the Omicron variant, which comprises the majority of cases in the U.S.
Researchers around the world have reported that Omicron is more transmissible than Delta, making breakthrough and repeat infections more likely.
The United States as of May 4 reached 996,145 COVID-19-related deaths and 81.5 million COVID-19 cases, according to Johns Hopkins University. Currently, 66.2% of the population is fully vaccinated, and 45.9% of vaccinated people have received booster doses.
Stacker compiled a list of the counties with highest COVID-19 infection rates in South Carolina using data from the U.S. Department of Health & Human Services and vaccination data from Covid Act Now. Counties are ranked by the highest infection rate per 100,000 residents within the week leading up to May 3, 2022. Cumulative cases per 100,000 served as a tiebreaker.
Keep reading to see whether your county ranks among the highest COVID-19 infection rates in your state.
#46. Hampton County, SC
Updated
- New cases per 100k in the past week: 5 (1 new cases, -50% change from previous week)
- Cumulative cases per 100k: 26,074 (5,012 total cases)
--- 8.9% less cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 447 (86 total deaths)
--- 29.6% more deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 64.2% (12,344 fully vaccinated)
#45. Lee County, SC
Updated
- New cases per 100k in the past week: 6 (1 new cases, -50% change from previous week)
- Cumulative cases per 100k: 25,279 (4,254 total cases)
--- 11.7% less cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 565 (95 total deaths)
--- 63.8% more deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 48.2% (8,111 fully vaccinated)
#44. Colleton County, SC
Updated
- New cases per 100k in the past week: 8 (3 new cases, -75% change from previous week)
- Cumulative cases per 100k: 23,526 (8,864 total cases)
--- 17.8% less cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 584 (220 total deaths)
--- 69.3% more deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 48.6% (18,325 fully vaccinated)
#43. Saluda County, SC
Updated
- New cases per 100k in the past week: 10 (2 new cases, +100% change from previous week)
- Cumulative cases per 100k: 19,333 (3,958 total cases)
--- 32.5% less cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 371 (76 total deaths)
--- 7.5% more deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 30.4% (6,230 fully vaccinated)
#42. Barnwell County, SC
Updated
- New cases per 100k in the past week: 10 (2 new cases, +100% change from previous week)
- Cumulative cases per 100k: 27,868 (5,815 total cases)
--- 2.7% less cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 489 (102 total deaths)
--- 41.7% more deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 56.5% (11,784 fully vaccinated)
#41. Williamsburg County, SC
Updated
- New cases per 100k in the past week: 10 (3 new cases, +50% change from previous week)
- Cumulative cases per 100k: 28,092 (8,531 total cases)
--- 1.9% less cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 481 (146 total deaths)
--- 39.4% more deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 57.4% (17,437 fully vaccinated)
#40. Darlington County, SC
Updated
- New cases per 100k in the past week: 12 (8 new cases, +33% change from previous week)
- Cumulative cases per 100k: 28,369 (18,899 total cases)
--- 0.9% less cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 465 (310 total deaths)
--- 34.8% more deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 48.9% (32,605 fully vaccinated)
#39. Jasper County, SC
Updated
- New cases per 100k in the past week: 13 (4 new cases, 0% change from previous week)
- Cumulative cases per 100k: 19,609 (5,897 total cases)
--- 31.5% less cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 309 (93 total deaths)
--- 10.4% less deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 37.8% (11,367 fully vaccinated)
#38. Marion County, SC
Updated
- New cases per 100k in the past week: 13 (4 new cases, -20% change from previous week)
- Cumulative cases per 100k: 27,883 (8,548 total cases)
--- 2.6% less cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 528 (162 total deaths)
--- 53.0% more deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 49.1% (15,047 fully vaccinated)
#37. Bamberg County, SC
Updated
- New cases per 100k in the past week: 14 (2 new cases, 0% change from previous week)
- Cumulative cases per 100k: 24,364 (3,427 total cases)
--- 14.9% less cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 533 (75 total deaths)
--- 54.5% more deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 51.4% (7,226 fully vaccinated)
#36. Marlboro County, SC
Updated
- New cases per 100k in the past week: 15 (4 new cases, +33% change from previous week)
- Cumulative cases per 100k: 30,094 (7,860 total cases)
--- 5.1% more cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 402 (105 total deaths)
--- 16.5% more deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 44.0% (11,498 fully vaccinated)
#35. Abbeville County, SC
Updated
- New cases per 100k in the past week: 16 (4 new cases, +100% change from previous week)
- Cumulative cases per 100k: 27,105 (6,648 total cases)
--- 5.3% less cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 281 (69 total deaths)
--- 18.6% less deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 40.1% (9,836 fully vaccinated)
#34. Florence County, SC
Updated
- New cases per 100k in the past week: 18 (25 new cases, +39% change from previous week)
- Cumulative cases per 100k: 30,197 (41,761 total cases)
--- 5.5% more cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 453 (626 total deaths)
--- 31.3% more deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 55.2% (76,371 fully vaccinated)
#33. Chesterfield County, SC
Updated
- New cases per 100k in the past week: 20 (9 new cases, +29% change from previous week)
- Cumulative cases per 100k: 25,884 (11,816 total cases)
--- 9.6% less cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 416 (190 total deaths)
--- 20.6% more deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 37.0% (16,908 fully vaccinated)
#32. Dillon County, SC
Updated
- New cases per 100k in the past week: 20 (6 new cases, 0% change from previous week)
- Cumulative cases per 100k: 31,858 (9,710 total cases)
--- 11.3% more cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 469 (143 total deaths)
--- 35.9% more deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 44.8% (13,667 fully vaccinated)
#31. Calhoun County, SC
Updated
- New cases per 100k in the past week: 21 (3 new cases, -40% change from previous week)
- Cumulative cases per 100k: 19,185 (2,792 total cases)
--- 33.0% less cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 419 (61 total deaths)
--- 21.4% more deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 41.2% (5,992 fully vaccinated)
#30. McCormick County, SC
Updated
- New cases per 100k in the past week: 21 (2 new cases, -75% change from previous week)
- Cumulative cases per 100k: 23,629 (2,236 total cases)
--- 17.5% less cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 423 (40 total deaths)
--- 22.6% more deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 59.0% (5,581 fully vaccinated)
#29. Laurens County, SC
Updated
- New cases per 100k in the past week: 22 (15 new cases, +88% change from previous week)
- Cumulative cases per 100k: 27,606 (18,632 total cases)
--- 3.6% less cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 436 (294 total deaths)
--- 26.4% more deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 38.7% (26,123 fully vaccinated)
#28. Chester County, SC
Updated
- New cases per 100k in the past week: 22 (7 new cases, +75% change from previous week)
- Cumulative cases per 100k: 31,324 (10,100 total cases)
--- 9.4% more cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 471 (152 total deaths)
--- 36.5% more deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 46.2% (14,910 fully vaccinated)
#27. Allendale County, SC
Updated
- New cases per 100k in the past week: 23 (2 new cases, -50% change from previous week)
- Cumulative cases per 100k: 24,010 (2,086 total cases)
--- 16.1% less cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 276 (24 total deaths)
--- 20.0% less deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 58.8% (5,112 fully vaccinated)
#26. Orangeburg County, SC
Updated
- New cases per 100k in the past week: 24 (21 new cases, +62% change from previous week)
- Cumulative cases per 100k: 27,069 (23,327 total cases)
--- 5.5% less cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 484 (417 total deaths)
--- 40.3% more deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 56.1% (48,314 fully vaccinated)
#25. Greenwood County, SC
Updated
- New cases per 100k in the past week: 25 (18 new cases, +64% change from previous week)
- Cumulative cases per 100k: 31,874 (22,570 total cases)
--- 11.3% more cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 429 (304 total deaths)
--- 24.3% more deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 48.3% (34,170 fully vaccinated)
#24. Fairfield County, SC
Updated
- New cases per 100k in the past week: 27 (6 new cases, +100% change from previous week)
- Cumulative cases per 100k: 26,755 (5,979 total cases)
--- 6.6% less cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 479 (107 total deaths)
--- 38.8% more deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 64.7% (14,459 fully vaccinated)
#23. Union County, SC
Updated
- New cases per 100k in the past week: 29 (8 new cases, +60% change from previous week)
- Cumulative cases per 100k: 28,331 (7,739 total cases)
--- 1.1% less cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 542 (148 total deaths)
--- 57.1% more deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 41.9% (11,445 fully vaccinated)
#22. Newberry County, SC
Updated
- New cases per 100k in the past week: 29 (11 new cases, 0% change from previous week)
- Cumulative cases per 100k: 34,579 (13,292 total cases)
--- 20.8% more cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 499 (192 total deaths)
--- 44.6% more deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 52.7% (20,250 fully vaccinated)
#21. Cherokee County, SC
Updated
- New cases per 100k in the past week: 30 (17 new cases, +42% change from previous week)
- Cumulative cases per 100k: 25,670 (14,709 total cases)
--- 10.4% less cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 558 (320 total deaths)
--- 61.7% more deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 34.4% (19,707 fully vaccinated)
#20. Spartanburg County, SC
Updated
- New cases per 100k in the past week: 31 (98 new cases, +17% change from previous week)
- Cumulative cases per 100k: 29,728 (95,065 total cases)
--- 3.8% more cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 483 (1,543 total deaths)
--- 40.0% more deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 44.0% (140,625 fully vaccinated)
#19. Edgefield County, SC
Updated
- New cases per 100k in the past week: 33 (9 new cases, +350% change from previous week)
- Cumulative cases per 100k: 24,820 (6,766 total cases)
--- 13.3% less cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 253 (69 total deaths)
--- 26.7% less deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 60.2% (16,402 fully vaccinated)
#18. Sumter County, SC
Updated
- New cases per 100k in the past week: 36 (38 new cases, +15% change from previous week)
- Cumulative cases per 100k: 26,126 (27,882 total cases)
--- 8.8% less cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 366 (391 total deaths)
--- 6.1% more deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 57.2% (61,051 fully vaccinated)
#17. Anderson County, SC
Updated
- New cases per 100k in the past week: 36 (72 new cases, +112% change from previous week)
- Cumulative cases per 100k: 28,558 (57,847 total cases)
--- 0.3% less cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 490 (993 total deaths)
--- 42.0% more deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 40.6% (82,199 fully vaccinated)
#16. Pickens County, SC
Updated
- New cases per 100k in the past week: 39 (50 new cases, -4% change from previous week)
- Cumulative cases per 100k: 36,208 (45,942 total cases)
--- 26.5% more cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 495 (628 total deaths)
--- 43.5% more deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 46.8% (59,412 fully vaccinated)
#15. Berkeley County, SC
Updated
- New cases per 100k in the past week: 41 (93 new cases, +24% change from previous week)
- Cumulative cases per 100k: 22,785 (51,928 total cases)
--- 20.4% less cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 197 (448 total deaths)
--- 42.9% less deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 52.4% (119,371 fully vaccinated)
#14. Clarendon County, SC
Updated
- New cases per 100k in the past week: 41 (14 new cases, +40% change from previous week)
- Cumulative cases per 100k: 25,912 (8,744 total cases)
--- 9.5% less cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 465 (157 total deaths)
--- 34.8% more deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 49.3% (16,638 fully vaccinated)
#13. Lancaster County, SC
Updated
- New cases per 100k in the past week: 42 (41 new cases, +86% change from previous week)
- Cumulative cases per 100k: 25,633 (25,123 total cases)
--- 10.5% less cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 287 (281 total deaths)
--- 16.8% less deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 46.4% (45,504 fully vaccinated)
#12. Georgetown County, SC
Updated
- New cases per 100k in the past week: 45 (28 new cases, +250% change from previous week)
- Cumulative cases per 100k: 25,327 (15,875 total cases)
--- 11.5% less cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 361 (226 total deaths)
--- 4.6% more deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 54.7% (34,256 fully vaccinated)
#11. Beaufort County, SC
Updated
- New cases per 100k in the past week: 47 (90 new cases, +22% change from previous week)
- Cumulative cases per 100k: 22,496 (43,220 total cases)
--- 21.4% less cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 196 (376 total deaths)
--- 43.2% less deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 65.8% (126,366 fully vaccinated)
#10. Greenville County, SC
Updated
- New cases per 100k in the past week: 47 (248 new cases, +57% change from previous week)
- Cumulative cases per 100k: 32,985 (172,688 total cases)
--- 15.2% more cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 381 (1,996 total deaths)
--- 10.4% more deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 55.6% (291,046 fully vaccinated)
#9. Dorchester County, SC
Updated
- New cases per 100k in the past week: 49 (80 new cases, +43% change from previous week)
- Cumulative cases per 100k: 34,422 (56,042 total cases)
--- 20.2% more cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 303 (494 total deaths)
--- 12.2% less deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 53.6% (87,282 fully vaccinated)
#8. Kershaw County, SC
Updated
- New cases per 100k in the past week: 50 (33 new cases, -28% change from previous week)
- Cumulative cases per 100k: 32,330 (21,516 total cases)
--- 12.9% more cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 385 (256 total deaths)
--- 11.6% more deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 58.9% (39,220 fully vaccinated)
#7. Aiken County, SC
Updated
- New cases per 100k in the past week: 51 (87 new cases, +412% change from previous week)
- Cumulative cases per 100k: 24,328 (41,569 total cases)
--- 15.0% less cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 256 (437 total deaths)
--- 25.8% less deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 46.2% (78,876 fully vaccinated)
#6. York County, SC
Updated
- New cases per 100k in the past week: 52 (147 new cases, +40% change from previous week)
- Cumulative cases per 100k: 27,686 (77,793 total cases)
--- 3.3% less cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 239 (672 total deaths)
--- 30.7% less deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 49.7% (139,742 fully vaccinated)
#5. Oconee County, SC
Updated
- New cases per 100k in the past week: 52 (41 new cases, +52% change from previous week)
- Cumulative cases per 100k: 30,470 (24,238 total cases)
--- 6.4% more cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 426 (339 total deaths)
--- 23.5% more deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 45.2% (35,928 fully vaccinated)
#4. Lexington County, SC
Updated
- New cases per 100k in the past week: 52 (154 new cases, +62% change from previous week)
- Cumulative cases per 100k: 32,114 (95,940 total cases)
--- 12.2% more cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 290 (866 total deaths)
--- 15.9% less deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 55.8% (166,760 fully vaccinated)
#3. Horry County, SC
Updated
- New cases per 100k in the past week: 55 (193 new cases, +77% change from previous week)
- Cumulative cases per 100k: 27,312 (96,705 total cases)
--- 4.6% less cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 326 (1,156 total deaths)
--- 5.5% less deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 56.7% (200,851 fully vaccinated)
#2. Richland County, SC
Updated
- New cases per 100k in the past week: 56 (233 new cases, +51% change from previous week)
- Cumulative cases per 100k: 29,501 (122,652 total cases)
--- 3.0% more cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 227 (943 total deaths)
--- 34.2% less deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 59.5% (247,217 fully vaccinated)
#1. Charleston County, SC
Updated
- New cases per 100k in the past week: 59 (244 new cases, +36% change from previous week)
- Cumulative cases per 100k: 27,291 (112,277 total cases)
--- 4.7% less cases per 100k residents than South Carolina
- Cumulative deaths per 100k: 228 (939 total deaths)
--- 33.9% less deaths per 100k residents than South Carolina
- Population that is fully vaccinated: 65.8% (270,536 fully vaccinated)
Originally published on stacker.com, part of the TownNews Content Exchange.
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